Latest Insights into Nutrition and COVID-19 Prevention

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Stress management, reduced stigma around obesity, healthy intakes of selenium, vitamin D and zinc, and a healthy gut microbiota… These were all highlighted as potential contributors to the fight against the effects of COVID-19 by expert scientists at the British Nutrition Foundation (BNF)’s virtual conference: Nutrition and COVID-19.  The conference took place on Tuesday 24th November 2020.

Eminent speakers working in the field of nutrition science discussed new and emerging research on the role nutrition plays – both in protecting against COVID-19 infection and in reducing the severity of associated health complications.

With the need for everyone to be more proactive about taking greater care of their own heath, I share some of the more interesting discussion points and conclusions.

Nutrients and Immunity

Prof Philip Calder at The University of Southampton explained that a well-functioning immune system is key to providing strong defence against infections such as COVID-19. He highlighted vitamin D, zinc and selenium as being important for anti-viral immunity:

Zinc
Calder emphasised the various roles zinc plays in the immune system and its specific function in preventing multiplication of single-strand RNA viruses, like Coronavirus, by inhibiting the enzymes they require to spread. Meat, poultry, cheese, shellfish, nuts, seeds and wholegrains provide natural sources of zinc.

Selenium
Selenium-deficiency can impair immune responses; increase susceptibility to viral infection; permit viruses to mutate; and allow weak viruses to become stronger. Calder shared previous research that suggests selenium supplementation in humans can help prevent viral mutation.   Poultry, fish, eggs, nuts, seeds and organ meats provide natural sources of selenium.

Vitamin D
Data suggests that low levels of vitamin D are associated with increased risk of COVID-19 infection, as well as hospitalisation. Calder stressed that this is an association and so does not provide evidence of causation and that there is currently not enough data available to recommend vitamin D for prevention of COVID-19.

Prof Susan Lanham-New at The University of Surrey, who reviewed the evidence on vitamin D, concurred but highlighted the importance of vitamin D for bones and muscles in the context of widespread low vitamin D status in the UK.  Lanham-New emphasised that all members of the public should take the recommended daily vitamin D supplement of 10 micrograms between October and March as a precaution to ensure good bone and muscle health.   

Long overdue, the Government has in the past 24-hours committed to offering free vitamin D to 2.5 million of the most vulnerable in England and those in care homes.

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“Maintaining a healthy, balanced diet, including foods from all the main food groups, is the best way to help ensure you get all of the nutrients you need for a healthy immune system. However, everyone should consider taking a vitamin D supplement especially during the winter months and also during the summer months if they are spending more time indoors than usual.”

Sara Stanner, Science Director – BNF

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The Effect of Probiotics and Prebiotics on COVID-19 Symptoms

Prof Glenn Gibson at The University of Reading presented the “Emerging evidence for the role of the human gut microbiome in COVID-19 infection outcomes” . He explored the potential for probiotics and prebiotics to support the gut microbiome in fighting COVID-19.

The gut microbiome is a harbouring site for COVID-19 and clinical outcomes can be governed by the type of gut microbiome the patient has. If numbers of ‘good bacteria’ in the gut are low it can be more difficult for that individual to fight off the virus.  

Gibson shared promising results from a recent Italian study into the effect of probiotics on the recovery of patients with COVID-19. The study involved two groups of people. The control group was given hydroxychloroquine, antibiotics, and tocilizumab, alone or in combination. The second group was given the same treatment but with a specific formulation of probiotics added. Within 72 hours, nearly all patients treated with probiotics showed remission of diarrhoea and other symptoms. This compared to less than half in the control group and there was also reduced admission to ICU and fewer deaths. More research is needed to confirm these findings.  

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The Mental Health Impact of Obesity and COVID-19 Risk

In the talk ‘Obesity as a risk factor for COVID-19’ ,  Prof Jason Halford at The University of Leeds, presented evidence to show that people living with obesity have an increased risk of contracting the virus, hospitalisation, ICU admission and dying from COVID-19.
 
The European Coalition for People Living with Obesity conducted a survey which Halford shared. The survey revealed that 73 percent of respondents are concerned about COVID-19 due to their weight. However, 43 percent have also been comfort or binge eating since the beginning of the pandemic; 60 percent are experiencing low levels of motivation; and 60 percent are struggling daily with their mental health.
 
Halford emphasised the negative impact that unusual life events can have on weight gain. Events like quarantine and being under lockdown. He highlighted that many weight management services have been de-prioritised due to the pandemic.  As such, stigma around obesity, particularly on social media and in the press, is unhelpful in improving public health. Instead, strategies for supporting good mental health are needed to help the weight loss efforts of those living with obesity.

“This year we have all faced a plethora of new challenges, and mental health issues are often the silent symptom of this pandemic. It’s therefore important for us all to recognise that we are living through an extremely stressful time, not to be too hard on ourselves, to look for support in finding ways to manage stress and to eat as healthily as we can”

Sara Stanner, Science Director – BNF

A growing number of resources with information and advice on diet and COVID-19 can be found on the BNF’s website.

To complete an online Creyos Health Cognitive Health assessment and organise a nutrition consultation with Charlotte Fraser Naturopathic Nutrition, email: enquiries@naturopathic-nutrition.com.

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Back to School Nutrition Tips For Health Prevention

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After six months of homeschool and two days back at school, my 9 year old put in an impressive 90 minutes of homework last night… developing a cough.

“I have a cough Mummy. EHH… KKHHH.. KKUHGH… I will need to quarantine for two weeks at home,” he announced. This was all accompanied by a lot of grunting, like he was trying to swallow a rubber.

I resorted to the first line in my ‘Differential Diagnosis’ manual and recommended he take a spoonful of honey and go to bed early. This provoked an immediate recovery much to everyone’s relief. Of course, the symptoms just happened to coincide with the launch of a new season on his Xbox. Enough said!

The whole ‘back to school’ is extra challenging for teachers and parents this year. September is the start of cold and flu season and now we have Covid-19 to contend with. With everyone on high alert for Covid-19 symptoms, how do you differentiate between these and an ordinary cough and cold? The answer is you can’t easily, especially with diarrhoea and vomiting now also reported as a Covid symptom in children. These symptoms are all part and parcel of school life at this time of year.

While we sadly can’t magic Covid-19 away, we can build our natural defences to benefit our overall physical, emotional and mental wellbeing.

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Prevention is Better than Cure

We all need to do as much as we can to build our immune defences to protect our community and bubbles. There is only so much that the Government, the NHS and our schools can do. Ultimately, everyone has to take more responsibility for their own health and I wish this message of self-care was integrated more into Government strategy. There needs to be a more preventative national health policy, one that extends beyond hand washing, mask wearing and social distancing. There are some early steps to address the UK’s high obesity levels evidenced in higher Covid complications and death rates. Again, however, making more gastric band surgery available on the NHS isn’t the solution, let’s do more to prevent obesity.

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Back to School Basics: Ways to Strengthen your Immune System

As well as protecting yourself from viruses on the outside, you can build up your body’s defences from the inside by strengthening your immune system. What you eat is pivotal to this as 70% of your immune system is in your gut. Here are some tips:

  • Make sure your diet is as varied as possible. Variety and balance are integral to optimal health and building up your immune system. So don’t go crazy for one fruit or vegetable that is particularly high in a certain nutrient. Aim to have 5-7 different plants a day at a ratio of 1 fruit for every 4 vegetables ideally. Ensure you have more vegetables than fruits, go for a rainbow of colours on the plate. The more varied your diet, the more you feed the good bacteria in your gut microbiome – your natural defence system. You are also more likely to get the full spectrum of nutrients and micronutrients that you need.

  • Eat foods which contain microbiome-enriching good bacteria such as kefir, natural bio yoghurt, certain cheeses and fermented foods. For a more in-depth analysis as to the important role of probiotics in strengthening our immune system click here. There is also a list of good bacteria-friendly foods.
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  • Keep an eye on your Zinc levels. This mineral helps develop white blood cells, the immune cells that fight off foreign bacteria and viruses. Zinc also helps protect the mucous membranes that coat the nose, throat, lungs and digestive tract – the entry points for Covid-19. I especially look out for zinc deficiency around puberty as Zinc is involved in numerous aspects of cellular metabolism that influence growth and maturation. Puberty pulls on your Zinc reserves more. Look out for possible signs of deficiency: white spots on the nails, spotty skin, acne, constipation, IBS, obsessive or stuck behaviour, and a more ‘glass half empty’ outlook.

    As well as being important for respiratory and gut health, Zinc is also an important mineral for your brain; Zinc deficiency is often implicated in my cognitive health and depression cases. If you supplement with Zinc it is best to choose a supplement such as Cytoplan’s Zinc & Copper; Zinc and Copper compete for the same absorption sites and too much of one can deplete the other. Similarly, ensure you get sufficient iron from natural food sources such as lean meat, spinach, lentils, apricots and eggs. Natural food sources high in zinc are oysters and shellfish, lean meat, pumpkin and other seeds.
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  • Watch your Vitamin D levels as this vitamin plays an important role in immune function. It is a common deficiency in the UK. Scientists are considering vitamin D supplementation as a preventive or therapeutic agent for severe COVID-19. They are researching Vitamin D deficiency as a possible risk factor. The body creates vitamin D from direct sunlight on the skin when outdoors. I recommend supplementation if you have dark skin which absorbs sunlight less easily or if you don’t get enough sunlight from October to March. Good natural food sources otherwise include: oily fish (salmon, trout, sardines, mackerel, herring, tuna and anchovies) and egg yolks.

  • Oily fish is important for brain and heart health. It is rich in omega-3 polyunsaturated fatty acids, which have been shown to reduce inflammation.
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  • Vitamin C is water-soluble: you don’t store it in your body and so you need to factor this into your daily diet. It is a common supplement but I encourage clients to get their Vitamin C in natural food sources. Bioflavonoids naturally accompany vitamin C in fruit and vegetables.  Vitamin C contributes to normal immune system function, and, as an antioxidant, the protection of cells from oxidative stress. It’s also important for bone and tooth formation, collagen production, Iodine conservation, wound healing , red blood cell formation, and infection resistance. Natural food sources include citrus fruits, kiwi fruit, Honeydew melon, potatoes, green peppers, broccoli, papayas, strawberries, rosehips, blackcurrants and tomatoes.

Do I Need to Supplement?

Nutrient shortfalls are caused by a number of different factors. Most people aren’t getting the essential nutrients they need for health and protection on a daily basis.

The following contribute to the nutritional ‘bank balance’ of our bodies and need to be factored into the equation:

  • Individual food choices
  • Food growing, processing and preparation methods
  • The actual nutrient content of the food you eat
  • The ability of you body to assimilate these nutrients
  • Lifestyle factors, such as stress and medications etc.
  • Activity levels and energy-expenditure
  • Certain life-stages, e,g. puberty where there is increased hormonal activity and growth

It isn’t always easy to determine what your child is eating in school dinners. And, a lot of school pack lunches lack the important variety factor so essential for good health. That’s when supplementation may be helpful.

Nutri-Bears is a good all-round wholefood supplement for primary school children who are fussy-eaters. For teenagers and young adults, Little People is a good option if you are looking for an additional layer of baseline support during the colder months.

All products referenced are available at www.cytoplan.co.uk. They supply science-based Food State and Wholefood nutritional supplements.

Please note that supplements aren’t a substitute for a healthy, varied diet. Keep introducing new plants and wholefoods to the mix and have fun experimenting with different textures and flavours. This really is the best recipe for optimum health.

If you have an underlying health condition or are on medication, I will be happy to provide more tailored advice for you. You should also consult your GP.

Contact Charlotte Fraser today to book a Nutrition Consultation.

Covid-19: Can Probiotics Help Calm the Storm?

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As the global science community races to develop an effective vaccine to stop the Coronovirus pandemic, a recent article in The Korean Bio-Medical Review caught my attention: ‘Korean researchers found substance inhibiting COVID-19’.   At the time, I was researching the digestive symptoms some Covid-19 patients are reporting, as well as looking for the latest scientific research into probiotics. 

Good bacteria and probiotics were a very new field of scientific study when I first qualified as a nutritional therapist but I credit these microbes for helping me to transform my own health and to manage my Ulcerative Colitis.

The Korean scientific study claims that Sea Buckthorn Berry’s lactic acid bacteria can contain the spread of the new coronavirus by inhibiting the activation of its energy source.  More specifically, the probiotic bacteria extracted from fermented Sea Buckthorn Berry had lots of lactobaciullus gasseri (L.gasseri) and this repressed the activation of purine which the new coronavirus requires to mutate.     Purine is a base (such as adenine or guanine) that is a constituent of DNA or RNA.

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In China, a separate research team led by Professor Ruan Jishou from Nankai University in Tianjin recently discovered that COVID-19 in the human body mutated in a similar way to the Ebola and AIDS virus. According to the Chinese research team, Covid-19 creates spike protein to survive within the human body. The spike protein contacts the cell membrane and attacks purine to acquire energy for its replication.

Notably, Korea is also using AIDS drugs to treat COVID-19 patients by inhibiting proteolytic enzyme activity. A patient’s symptoms improved significantly in a few days after administrating Kaletra and AIDS drugs. Professor Yoon expects the probiotic bacteria in Sea Buckthorn Berry to be a supplementary treatment to suppress COVID-19 spread.

Covid-19 and Cytokine Storms

Delving further into lactobacillus gasseri, I came across a separate study published in October 2019 in Frontiers in Immunology. Lactobacillus gasseri was found to suppress the production of proinflammatory cytokines in Helicobacter pylori-infected macrophages.

Cytokine storms are a common complication not only of Covid-19 and flu but of other respiratory diseases caused by coronaviruses such as SARS and MERS.

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Cytokines act as chemical messengers between cells and interact with cells of the immune system to regulate the body’s response to disease and infection, as well as mediate normal cellular processes in the body. They are important in both health and disease specific to the host’s response to infection, immune responses, inflammation, trauma, sepsis, cancer, and reproduction.

Diseases such as Covid-19 and influenza can be fatal due to an overreaction of the body’s immune system which can provoke a cytokine storm. This is when the body attacks itself, unable to distinguish itself from the enemy invader or virus. An overproduction of immune cells, and their signaling compounds (cytokines) can trigger hyper-inflammation and this can cause substantial tissue damage, an effect of many autoimmune disorders such as Lupus, Rheumatoid Arthritis, MS, Diabetes, Crohn’s Disease and Ulcerative Colitis.

What is lactobacillus gasseri?

A probiotic, Lactobacillus gasseri is a strain of the Lactobacillus family of bacteria naturally found in the digestive and urinary tracts. The bacteria is thought to help the body suppress harmful bacteria and to enhance immune function and aids in digestion. A number of clinical trials have suggested that Lactobacillus gasseri may also help reduce abdominal fat and support weight loss, as well as be beneficial for managing inflammatory bowel disease.

Covid-19: Strengthen your body’s natural defences

Aside from taking precautions to protect yourself from the virus on the outside, you can also build up your body’s defences from the inside by strengthening your immune system. Replenishing the gut with more good bacteria is really pivotal to this and it is something you can do even whilst you are staying at home on lockdown.

Tim Spector, Professor of Genetic Epidemiology at King’s College London, provided some useful insights in The Conversation this past month. Professor Spector explains that the immune system is complex with many factors affecting its function. However, “what’s important to know is that most of these factors are not hard-coded in our genes but are influenced by lifestyle and the world around us”.

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Professor Spector says “One thing that you can control immediately is the health of the trillions of microbes living in your gut, collectively known as the microbiome. Recent research has shown that the gut microbiome plays an essential role in the body’s immune response to infection and in maintaining overall health. As well as mounting a response to infectious pathogens like coronavirus, a healthy gut microbiome also helps to prevent potentially dangerous immune over-reactions that damage the lungs and other vital organs. These excessive immune responses can cause respiratory failure and death. (This is also why we should talk about “supporting” rather than “boosting” the immune system, as an overactive immune response can be as risky as an underactive one.)”

Professor Spector also explains that “Gut bacteria produce many beneficial chemicals and also activate vitamin A in food” and that these “help to regulate the immune system.” Vitamin A is sourced from betacarotene-rich fruit and vegetables such as carrots, sweet potato and squash – and of course, Sea Buckthorn Berry if you happen to live near the coast.

How can I strengthen my microbiome and boost my good bacteria?

Eating a wide range of plant based foods and limiting highly-processed foods is the best way to increase microbiome diversity – your good bacteria. Avoid junk food!

Professor Spector says: “Following a Mediterranean diet has also been shown to improve gut microbiome diversity and reduce inflammation: eating plenty of fruit, vegetables, nuts, seeds and whole grains; healthy fats like high-quality extra virgin olive oil; and lean meat or fish. Avoid alcohol, salt, sweets and sugary drinks, and artificial sweeteners or other additives.”

You an also eat foods which contain microbiome enriching good bacteria – probiotics.

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Kefir and Berries

Best Sources of lactobacillus gasseri and probiotics:

There is a variety of natural food sources for probiotics. Full fat live bio yogurt is the best known and this is milk fermented with specific Lactobacillus or Bifidobacterium strains.

Other fermented foods that contain good ‘health-promoting’ bacteria include:

  • Kefir (You can make your own but I like Chuckling Goat’s Probiotic Live Goat’s Milk Kefir which has 35 probiotic strains including lactobacillus gasseri. You can even add extract of Sea Buckthorn powder (a source of rare omega-7, beta-carotene and phytonutrients that work together to support your immunity, mucosa function and skin health), or fresh berries.
  • Kombucha (Wild Fizz’s Organic Lavender & Rosemary is a Kombucha that I particularly like and I have Jeannette Hyde, Author of The Gut Makeover to thank for introducing this to me (I recommend Jeannette’s recipes too!) Watch out for added sweeteners in a lot of the supermarket brands of Kombucha though).
  • Fermented, raw cheeses (Emmental, aged Gouda, Gruyere, Parmesan – look for the words “raw”, “probiotic,” or “made from raw milk” on the label. Remember, no cooking or melting if you want to preserve the probiotic benefits!
  • Sauerkraut
  • Raw apple cider vinegar
  • Kimchi
  • Natto
  • Miso
  • Tempeh

Probiotics and good bacteria can be beneficial for most people but you may need to avoid Lactobacillus if you have a compromised immune systems. Those with advanced HIV infection, those who are organ transplant recipients, and those taking immunosuppressive drugs for cancer and other conditions should consult a medical practitioner first.